As long as you are not running away but rather running toward a new opportunity, you will not regret it. Your GE career will have served you well. Yes, you will have to deal with navigating on-boarding and social norms of a new company (culture, size, industry, people) but in the end, you will likely be paid more money and gain a broader people network and be able to showcase what you have learned/contributed at GE at your next company. I miss my time at GE but do not regret leaving. Life is a continuum and it was time to continue on. I also ensured I was not leaving 'anything' on the table before accepting a new role outside of GE. Meaning, I didn't want to leave but felt the opportunities were shrinking based on my career goals - I met with a few trusted leaders and they, indirectly, confirmed what I knew...that I had outgrown the company based on my personal goals and circumstances (e.g. not being able to move to the locations where there were opportunities)
I agree with the points that @X4c2AJp-ezi made